By George M. Rodgers
This finished quantity discusses the protease ADAMTS13, summarizing the present prestige of easy and scientific learn. The 9 authoritative chapters start with a historic viewpoint by means of exploration of the biochemistry and structure-function relationships of ADAMTS13 in addition to its basic functionality in hemostasis (cleavage of von Willebrand factor). rising learn topics for ADAMTS13 are lined, together with its power function in angiogenesis and different points of cellphone biology. extra issues comprise laboratory assays for ADAMTS13, inherited ADAMTS13 deficiency, and purchased ADAMTS13 deficiency. A bankruptcy on similar thrombotic microangiopathic (TMA) issues examines the variations among TMAs linked to ADAMTS13 deficiency and people now not linked to ADAMTS13 deficiency. a last bankruptcy studies the initial details on rising elements of ADAMTS13, equivalent to the prestige of recombinant ADAMTS13 items and their strength utility.
Comprehensive in its exploration of the ADAMTS13 protease in disease, ADAMTS13: Biology and ailment is an important source for medical hematologists, transfusion drugs physicians, and researchers attracted to hemostasis, vascular biology, biochemistry, and metalloproteases.
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ADAMTS13: Biology and Disease by George M. Rodgers